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Hypoxia increases the expression of stem cell markers in human osteosarcoma cells

Osteosarcoma (OS) is the most common primary malignant tumor of bone. It is a common phenomenon that osteosarcoma cells have a hypoxic microenvironment. Hypoxia can dedifferentiate cells of several malignant tumor types into stem cell-like phenotypes. However, the role of hypoxia in stemness inducti...

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Detalles Bibliográficos
Autores principales: Lin, Jinluan, Wang, Xinwu, Wang, Xinwen, Wang, Shenglin, Shen, Rongkai, Yang, Yanbing, Xu, Jianyong, Lin, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856697/
https://www.ncbi.nlm.nih.gov/pubmed/33613706
http://dx.doi.org/10.3892/ol.2021.12478