Cargando…

Hypoxia increases the expression of stem cell markers in human osteosarcoma cells

Osteosarcoma (OS) is the most common primary malignant tumor of bone. It is a common phenomenon that osteosarcoma cells have a hypoxic microenvironment. Hypoxia can dedifferentiate cells of several malignant tumor types into stem cell-like phenotypes. However, the role of hypoxia in stemness inducti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Jinluan, Wang, Xinwu, Wang, Xinwen, Wang, Shenglin, Shen, Rongkai, Yang, Yanbing, Xu, Jianyong, Lin, Jianhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856697/ https://www.ncbi.nlm.nih.gov/pubmed/33613706 http://dx.doi.org/10.3892/ol.2021.12478

Ejemplares similares

Classification of Osteosarcoma Based on Immunogenomic Profiling
por: Wang, Xinwen, et al.
Publicado: (2021)

NLRP3 Overexpression Associated With Poor Prognosis and Presented as an Effective Therapeutic Target in Osteosarcoma
por: Huang, Zhen, et al.
Publicado: (2021)

Corrigendum: NLRP3 Overexpression Associated With Poor Prognosis and Presented as an Effective Therapeutic Target in Osteosarcoma
por: Huang, Zhen, et al.
Publicado: (2021)

Inhibition of BUB1 suppresses tumorigenesis of osteosarcoma via blocking of PI3K/Akt and ERK pathways
por: Huang, Zhen, et al.
Publicado: (2021)

Verification of TREX1 as a promising indicator of judging the prognosis of osteosarcoma
por: Feng, Jinyi, et al.
Publicado: (2016)

ACTN4 Promotes the Proliferation, Migration, Metastasis of Osteosarcoma and Enhances its Invasive Ability through the NF-κB Pathway
por: Huang, Qingshan, et al.
Publicado: (2019)

The Clinical Significance of the Expression of FEN1 in Primary Osteosarcoma
por: Zhong, Guangxian, et al.
Publicado: (2021)

A Nanodrug Consisting Of Doxorubicin And Exosome Derived From Mesenchymal Stem Cells For Osteosarcoma Treatment In Vitro
por: Wei, Hongxiang, et al.
Publicado: (2019)

Mesenchymal Stem Cell Derived Exosomes as Nanodrug Carrier of Doxorubicin for Targeted Osteosarcoma Therapy via SDF1-CXCR4 Axis
por: Wei, Hongxiang, et al.
Publicado: (2022)

The clinical significance of the Ezrin gene and circulating tumor cells in osteosarcoma
por: Zhong, Guang-Xian, et al.
Publicado: (2017)

RNA Sequencing of Osteosarcoma Gene Expression Profile Revealed that miR-214-3p Facilitates Osteosarcoma Cell Proliferation via Targeting Ubiquinol-Cytochrome c Reductase Core Protein 1 (UQCRC1)
por: Zhao, Xin, et al.
Publicado: (2019)

Enrichment of osteosarcoma stem cells by chemotherapy
por: Tang, Qing-Lian, et al.
Publicado: (2011)

Circular RNA expression pattern in cisplatin-resistant osteosarcoma cells
por: Han, Jianhua, et al.
Publicado: (2020)

Self‐assembled human placental model from trophoblast stem cells in a dynamic organ‐on‐a‐chip system
por: Cao, Rongkai, et al.
Publicado: (2023)

Overexpression of SENP1 reduces the stemness capacity of osteosarcoma stem cells and increases their sensitivity to HSVtk/GCV
por: Liu, Fengting, et al.
Publicado: (2018)

Overexpression of SENP1 reduces the stemness capacity of osteosarcoma stem cells and increases their sensitivity to HSVtk/GCV
por: Liu, Fengting, et al.
Publicado: (2019)

miR-596 suppresses the expression of Survivin and enhances the sensitivity of osteosarcoma cells to the molecular targeting agent anlotinib
por: Wang, Leisheng, et al.
Publicado: (2019)

Hypoxia-Inducible Factor 1A Upregulates HMGN5 by Increasing the Expression of GATA1 and Plays a Role in Osteosarcoma Metastasis
por: Xu, Enjie, et al.
Publicado: (2019)

Exosomes Secreted by Adipose-Derived Mesenchymal Stem Cells Foster Metastasis and Osteosarcoma Proliferation by Increasing COLGALT2 Expression
por: Wang, Yan, et al.
Publicado: (2020)

Increased SNAT1 is a marker of human osteosarcoma and potential therapeutic target
por: Wang, Miaomiao, et al.
Publicado: (2017)

LncRNA THOR increases osteosarcoma cell stemness and migration by enhancing SOX9 mRNA stability
por: Wu, Haojun, et al.
Publicado: (2019)

Cross-segment spinal plasma cell granuloma:a case report
por: Lin, Renqin, et al.
Publicado: (2020)

Clinical Significance of Cancer Stem Cell Markers CD133 and CXCR4 in Osteosarcomas
por: Mardani, Azam, et al.
Publicado: (2020)

Single-cell RNA sequencing identifies critical transcription factors of tumor cell invasion induced by hypoxia microenvironment in glioblastoma
por: Zhang, Yanru, et al.
Publicado: (2023)

Long noncoding RNA ANRIL is activated by hypoxia-inducible factor-1α and promotes osteosarcoma cell invasion and suppresses cell apoptosis upon hypoxia
por: Wei, Xiaokang, et al.
Publicado: (2016)

Hypoxia-induced autophagy as an additional mechanism in human osteosarcoma radioresistance
por: Feng, Helin, et al.
Publicado: (2016)

Targeting the osteosarcoma cancer stem cell
por: Siclari, Valerie A, et al.
Publicado: (2010)

A novel long non-coding RNA, hypoxia-inducible factor-2α promoter upstream transcript, functions as an inhibitor of osteosarcoma stem cells in vitro
por: WANG, YONGCHENG, et al.
Publicado: (2015)

An Immunogenic Cell Death-Related Classification Predicts Prognosis and Response to Immunotherapy in Head and Neck Squamous Cell Carcinoma
por: Wang, Xinwen, et al.
Publicado: (2021)

Heterogenic expression of stem cell markers in patient-derived glioblastoma spheroid cultures exposed to long-term hypoxia
por: Rosenberg, Tine, et al.
Publicado: (2018)

Hypoxia Increases Thyroid Cancer Stem Cell-Enriched Side Population
por: Mahkamova, K., et al.
Publicado: (2017)

miR-15a represses cancer cell migration and invasion under conditions of hypoxia by targeting and downregulating Bcl-2 expression in human osteosarcoma cells
por: Leng, Jiali, et al.
Publicado: (2018)

Bone marrow mesenchymal stem cells promote osteosarcoma cell proliferation and invasion
por: Yu, Fu-Xiang, et al.
Publicado: (2015)

Identification of Stem Cell Related Gene Expression from the Osteosarcoma Cell Core Side
por: Lim, Chaemoon, et al.
Publicado: (2022)

Delineation of hypoxia-induced proteome shifts in osteosarcoma cells with different metastatic propensities
por: Song, Zifeng, et al.
Publicado: (2020)

Retraction Note: Long noncoding RNA ANRIL is activated by hypoxia-inducible factor-1α and promotes osteosarcoma cell invasion and suppresses cell apoptosis upon hypoxia
por: Wei, Xiaokang, et al.
Publicado: (2017)

Prognostic role of hypoxia-inducible factor-1 alpha expression in osteosarcoma: a meta-analysis
por: Ren, Hai-Yong, et al.
Publicado: (2016)

The hypoxia-related signature predicts prognosis, pyroptosis and drug sensitivity of osteosarcoma
por: Hu, Lin, et al.
Publicado: (2022)

Exosomal HMGB1 derived from hypoxia‐conditioned bone marrow mesenchymal stem cells increases angiogenesis via the JNK/HIF‐1α pathway
por: Gao, Wenling, et al.
Publicado: (2021)

Increased expression of microRNA-148a in osteosarcoma promotes cancer cell growth by targeting PTEN
por: Zhang, Hao, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_gs3m4hloem41deae63b4ac2cl4