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MiR-140-3p inhibits the cell viability and promotes apoptosis of synovial fibroblasts in rheumatoid arthritis through targeting sirtuin 3

BACKGROUND: Synovial fibroblasts (SFs) with the abnormal expressions of miRNAs are the key regulator in rheumatoid arthritis (RA). Low-expressed miR-140-3p was found in RA tissues. Therefore, we attempted to investigate the effect of miR-140-3p on SFs of RA. METHODS: RA and normal synovial fibrous t...

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Detalles Bibliográficos
Autores principales: Zu, Beibei, Liu, Lin, Wang, Jingya, Li, Meirong, Yang, Junxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856785/
https://www.ncbi.nlm.nih.gov/pubmed/33530998
http://dx.doi.org/10.1186/s13018-021-02236-5