Hepatocyte ATF3 protects against atherosclerosis by regulating HDL and bile acid metabolism

Activating transcription factor 3 (ATF3) is known to have an anti-inflammatory function, yet the role of hepatic ATF3 in lipoprotein metabolism or atherosclerosis remains unknown. Here we show that over-expression of human ATF3 in hepatocytes reduces the development of atherosclerosis in Western die...

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Detalles Bibliográficos
Autores principales: Xu, Yanyong, Li, Yuanyuan, Jadhav, Kavita, Pan, Xiaoli, Zhu, Yingdong, Hu, Shuwei, Chen, Shaoru, Chen, Liuying, Tang, Yong, Wang, Helen H., Yang, Ling, Wang, David Q.-H., Yin, Liya, Zhang, Yanqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856821/
https://www.ncbi.nlm.nih.gov/pubmed/33462514
http://dx.doi.org/10.1038/s42255-020-00331-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856821/
https://www.ncbi.nlm.nih.gov/pubmed/33462514
http://dx.doi.org/10.1038/s42255-020-00331-1

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