Highly multiplexed oligonucleotide probe-ligation testing enables efficient extraction-free SARS-CoV-2 detection and viral genotyping

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There is an urgent and unprecedented need for sensitive and high-throughput molecular diagnostic tests to combat the SARS-CoV-2 pandemic. Here we present a generalized version of the RNA-mediated oligonucleotide Annealing Selection and Ligation with next generation DNA sequencing (RASL-seq) assay, c...

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Detalles Bibliográficos
Autores principales: Credle, Joel J., Robinson, Matthew L., Gunn, Jonathan, Monaco, Daniel, Sie, Brandon, Tchir, Alexandra, Hardick, Justin, Zheng, Xuwen, Shaw-Saliba, Kathryn, Rothman, Richard E., Eshleman, Susan H., Pekosz, Andrew, Hansen, Kasper, Mostafa, Heba, Steinegger, Martin, Larman, H. Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: United States & Canadian Academy of Pathology. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856856/
https://www.ncbi.nlm.nih.gov/pubmed/33536572
http://dx.doi.org/10.1038/s41379-020-00730-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856856/
https://www.ncbi.nlm.nih.gov/pubmed/33536572
http://dx.doi.org/10.1038/s41379-020-00730-5

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