TET2-Loss-of-Function-Driven Clonal Hematopoiesis Exacerbates Experimental Insulin Resistance in Aging and Obesity

Human aging is frequently accompanied by the acquisition of somatic mutations in the hematopoietic system that induce clonal hematopoiesis, leading to the development of a mutant clone of hematopoietic progenitors and leukocytes. This somatic-mutation-driven clonal hematopoiesis has been associated...

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Detalles Bibliográficos
Autores principales: Fuster, José J., Zuriaga, María A., Zorita, Virginia, MacLauchlan, Susan, Polackal, Maya N., Viana-Huete, Vanesa, Ferrer-Pérez, Alba, Matesanz, Nuria, Herrero-Cervera, Andrea, Sano, Soichi, Cooper, Matthew A., González-Navarro, Herminia, Walsh, Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856871/
https://www.ncbi.nlm.nih.gov/pubmed/33113366
http://dx.doi.org/10.1016/j.celrep.2020.108326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856871/
https://www.ncbi.nlm.nih.gov/pubmed/33113366
http://dx.doi.org/10.1016/j.celrep.2020.108326

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