GBP1 Facilitates Indoleamine 2,3-Dioxygenase Extracellular Secretion to Promote the Malignant Progression of Lung Cancer

IDO1-mediated immune escape can lead to the malignant progression of tumors. However, the precise mechanism of IDO1 remains unclear. This study showed that IDO1 can bind to GBP1 and increase the extracellular secretion of IDO1 with the assistance of GBP1, thereby promoting the malignant proliferatio...

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Detalles Bibliográficos
Autores principales: Meng, Yinnan, Wang, Wei, Chen, Meng, Chen, Kuifei, Xia, Xinhang, Zhou, Suna, Yang, Haihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857027/
https://www.ncbi.nlm.nih.gov/pubmed/33552086
http://dx.doi.org/10.3389/fimmu.2020.622467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857027/
https://www.ncbi.nlm.nih.gov/pubmed/33552086
http://dx.doi.org/10.3389/fimmu.2020.622467

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