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Versatile and multivalent nanobodies efficiently neutralize SARS-CoV-2

Cost-effective, efficacious therapeutics are urgently needed to combat the COVID-19 pandemic. In this study, we used camelid immunization and proteomics to identify a large repertoire of highly potent neutralizing nanobodies (Nbs) to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) s...

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Detalles Bibliográficos
Autores principales: Xiang, Yufei, Nambulli, Sham, Xiao, Zhengyun, Liu, Heng, Sang, Zhe, Duprex, W. Paul, Schneidman-Duhovny, Dina, Zhang, Cheng, Shi, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857400/
https://www.ncbi.nlm.nih.gov/pubmed/33154108
http://dx.doi.org/10.1126/science.abe4747