Chromosomal localization of Ewing sarcoma EWSR1/FLI1 protein promotes the induction of aneuploidy

Ewing sarcoma is a pediatric bone cancer that expresses the chimeric protein EWSR1/FLI1. We previously demonstrated that EWSR1/FLI1 impairs the localization of Aurora B kinase to the midzone (the midline structure located between segregating chromosomes) during anaphase. While localization of Aurora...

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Detalles Bibliográficos
Autores principales: Park, Hyewon, Kim, Haeyoung, Hassebroek, Victoria, Azuma, Yoshiaki, Slawson, Chad, Azuma, Mizuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857440/
https://www.ncbi.nlm.nih.gov/pubmed/33293370
http://dx.doi.org/10.1074/jbc.RA120.014328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857440/
https://www.ncbi.nlm.nih.gov/pubmed/33293370
http://dx.doi.org/10.1074/jbc.RA120.014328

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