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Chromosomal localization of Ewing sarcoma EWSR1/FLI1 protein promotes the induction of aneuploidy
Ewing sarcoma is a pediatric bone cancer that expresses the chimeric protein EWSR1/FLI1. We previously demonstrated that EWSR1/FLI1 impairs the localization of Aurora B kinase to the midzone (the midline structure located between segregating chromosomes) during anaphase. While localization of Aurora...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857440/ https://www.ncbi.nlm.nih.gov/pubmed/33293370 http://dx.doi.org/10.1074/jbc.RA120.014328 |