Hyper-truncated Asn355- and Asn391-glycans modulate the activity of neutrophil granule myeloperoxidase

Myeloperoxidase (MPO) plays essential roles in neutrophil-mediated immunity via the generation of reactive oxidation products. Complex carbohydrates decorate MPO at discrete sites, but their functional relevance remains elusive. To this end, we have characterised the structure–biosynthesis–activity...

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Detalles Bibliográficos
Autores principales: Tjondro, Harry C., Ugonotti, Julian, Kawahara, Rebeca, Chatterjee, Sayantani, Loke, Ian, Chen, Siyun, Soltermann, Fabian, Hinneburg, Hannes, Parker, Benjamin L., Venkatakrishnan, Vignesh, Dieckmann, Regis, Grant, Oliver C., Bylund, Johan, Rodger, Alison, Woods, Robert J., Karlsson-Bengtsson, Anna, Struwe, Weston B., Thaysen-Andersen, Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857493/
https://www.ncbi.nlm.nih.gov/pubmed/33273015
http://dx.doi.org/10.1074/jbc.RA120.016342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857493/
https://www.ncbi.nlm.nih.gov/pubmed/33273015
http://dx.doi.org/10.1074/jbc.RA120.016342

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