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Multivalent lipid targeting by the calcium-independent C2A domain of synaptotagmin-like protein 4/granuphilin

Synaptotagmin-like protein 4 (Slp-4), also known as granuphilin, is a Rab effector responsible for docking secretory vesicles to the plasma membrane before exocytosis. Slp-4 binds vesicular Rab proteins via an N-terminal Slp homology domain, interacts with plasma membrane SNARE complex proteins via...

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Detalles Bibliográficos
Autores principales: Alnaas, Aml A., Watson-Siriboe, Abena, Tran, Sherleen, Negussie, Mikias, Henderson, Jack A., Osterberg, J. Ryan, Chon, Nara L., Harrott, Beckston M., Oviedo, Julianna, Lyakhova, Tatyana, Michel, Cole, Reisdorph, Nichole, Reisdorph, Richard, Shearn, Colin T., Lin, Hai, Knight, Jefferson D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857503/
https://www.ncbi.nlm.nih.gov/pubmed/33277360
http://dx.doi.org/10.1074/jbc.RA120.014618