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USP22 controls necroptosis by regulating receptor‐interacting protein kinase 3 ubiquitination

Dynamic control of ubiquitination by deubiquitinating enzymes is essential for almost all biological processes. Ubiquitin‐specific peptidase 22 (USP22) is part of the SAGA complex and catalyzes the removal of mono‐ubiquitination from histones H2A and H2B, thereby regulating gene transcription. Howev...

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Detalles Bibliográficos
Autores principales: Roedig, Jens, Kowald, Lisa, Juretschke, Thomas, Karlowitz, Rebekka, Ahangarian Abhari, Behnaz, Roedig, Heiko, Fulda, Simone, Beli, Petra, van Wijk, Sjoerd JL
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857539/
https://www.ncbi.nlm.nih.gov/pubmed/33369872
http://dx.doi.org/10.15252/embr.202050163