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Immune synapse instructs epigenomic and transcriptomic functional reprogramming in dendritic cells

Understanding the fate of dendritic cells (DCs) after productive immune synapses (postsynaptic DCs) with T cells during antigen presentation has been largely neglected in favor of deciphering the nuances of T cell activation and memory generation. Here, we describe that postsynaptic DCs switch their...

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Detalles Bibliográficos
Autores principales: Alcaraz-Serna, Ana, Bustos-Morán, Eugenio, Fernández-Delgado, Irene, Calzada-Fraile, Diego, Torralba, Daniel, Marina-Zárate, Ester, Lorenzo-Vivas, Erika, Vázquez, Enrique, de Alburquerque, Juliana Barreto, Ruef, Nora, Gómez, Manuel José, Sánchez-Cabo, Fátima, Dopazo, Ana, Stein, Jens V., Ramiro, Almudena, Sánchez-Madrid, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857677/
https://www.ncbi.nlm.nih.gov/pubmed/33536205
http://dx.doi.org/10.1126/sciadv.abb9965