Cargando…

Celsr1 adhesive interactions mediate the asymmetric organization of planar polarity complexes

To orchestrate collective polarization across tissues, planar cell polarity (PCP) proteins localize asymmetrically to cell junctions, a conserved feature of PCP that requires the atypical cadherin Celsr1. We report that mouse Celsr1 engages in both trans- and cis-interactions, and organizes into den...

Descripción completa

Detalles Bibliográficos
Autores principales: Stahley, Sara N, Basta, Lena P, Sharan, Rishabh, Devenport, Danelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857726/
https://www.ncbi.nlm.nih.gov/pubmed/33529151
http://dx.doi.org/10.7554/eLife.62097