Design and Synthesis of 4-O-Podophyllotoxin Sulfamate Derivatives as Potential Cytotoxic Agents

4-O-Podophyllotoxin sulfamate derivatives were prepared using the natural lignan podophyllotoxin. The prepared compounds were afforded by reacting O-sulfonyl chloride podophyllotoxin with ammonia or aminoaryl/heteroaryl motif. Biological evaluation was performed in human breast cancer (MCF7), ovaria...

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Detalles Bibliográficos
Autores principales: Bader, Ammar, Bkhaitan, Majdi M., Abdalla, Ashraf N., Abdallah, Qasem M. A., Ali, Hamed I., Sabbah, Dima A., Albadawi, Ghadeer, Abushaikha, Ghassan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857870/
https://www.ncbi.nlm.nih.gov/pubmed/33574882
http://dx.doi.org/10.1155/2021/6672807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857870/
https://www.ncbi.nlm.nih.gov/pubmed/33574882
http://dx.doi.org/10.1155/2021/6672807

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