Activation of Nrf2 by miR-152 Inhibits Doxorubicin-Induced Cardiotoxicity via Attenuation of Oxidative Stress, Inflammation, and Apoptosis

Doxorubicin (DOX) could trigger congestive heart failure, which largely limited the clinical use of DOX. microRNAs (miRNAs) were closely involved in the pathogenesis of DOX-induced cardiomyopathy. Here, we aimed to investigate the effect of miR-152 on DOX-induced cardiotoxicity in mice. To study thi...

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Detalles Bibliográficos
Autores principales: Zhang, Wen-Bin, Lai, Xin, Guo, Xu-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857911/
https://www.ncbi.nlm.nih.gov/pubmed/33574984
http://dx.doi.org/10.1155/2021/8860883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857911/
https://www.ncbi.nlm.nih.gov/pubmed/33574984
http://dx.doi.org/10.1155/2021/8860883

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