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Primary Cilia as a Biomarker in Mesenchymal Stem Cells Senescence: Influencing Osteoblastic Differentiation Potency Associated with Hedgehog Signaling Regulation

Bone tissue engineering-based therapy for bone lesions requires the expansion of seeding cells, such as autologous mesenchymal stem cells (MSCs). A major obstacle to this process is the loss of the phenotype and differentiation capacity of MSCs subjected to passage. Recent studies have suggested tha...

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Detalles Bibliográficos
Autores principales: Fu, Su, Zhang, Chunlin, Yan, Xu, Li, Dongzhe, Wang, Yongkui, Dong, Chao, Cao, Zhengming, Ning, Yongming, Shao, Chenglong, Yang, Tengyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857927/
https://www.ncbi.nlm.nih.gov/pubmed/33574852
http://dx.doi.org/10.1155/2021/8850114