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Pronounce expression of Tim-3 and CD39 but not PD1 defines CD8 T cells in critical Covid-19 patients

BACKGROUND: During viral infection, inhibitory receptors play a key role in regulating CD8 T-cell activity. The objective of this research was to investigate programmed cell death protein 1 (PD-1), T-cell immunoglobulin and mucin domain-containing protein-3 (TIM-3), and CD39 exhaustion markers in CD...

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Detalles Bibliográficos
Autores principales: Shahbazi, Mehdi, Moulana, Zahra, Sepidarkish, Mahdi, Bagherzadeh, Mojgan, Rezanejad, Maryam, Mirzakhani, Mohammad, Jafari, Mohammad, Mohammadnia-Afrouzi, Mousa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857983/
https://www.ncbi.nlm.nih.gov/pubmed/33548481
http://dx.doi.org/10.1016/j.micpath.2021.104779