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Letrozole and zoledronic acid changed signalling pathways involved in the apoptosis of breast cancer cells

OBJECTIVES: Oestrogen plays a key role in the development of breast malignancies. Therefore, aromatase inhibitors (e.g. letrozole [LTZ]) are widely used in the treatment of breast cancer. On the other hand, oestrogen is important to the integrity of bone mass. Research has shown that zoledronic acid...

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Detalles Bibliográficos
Autores principales: Sheweita, Salah A., Ammar, Rania G., Sabra, Sally A., Sultan, Ahmed S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taibah University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7858005/
https://www.ncbi.nlm.nih.gov/pubmed/33603639
http://dx.doi.org/10.1016/j.jtumed.2020.10.017