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Genetic Evidence for SecY Translocon-Mediated Import of Two Contact-Dependent Growth Inhibition (CDI) Toxins

The C-terminal (CT) toxin domains of contact-dependent growth inhibition (CDI) CdiA proteins target Gram-negative bacteria and must breach both the outer and inner membranes of target cells to exert growth inhibitory activity. Here, we examine two CdiA-CT toxins that exploit the bacterial general pr...

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Detalles Bibliográficos
Autores principales: Jones, Allison M., Virtanen, Petra, Hammarlöf, Disa, Allen, William J., Collinson, Ian, Hayes, Christopher S., Low, David A., Koskiniemi, Sanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7858069/
https://www.ncbi.nlm.nih.gov/pubmed/33531386
http://dx.doi.org/10.1128/mBio.03367-20