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Multiplex RNA‐based detection of clinically relevant MET alterations in advanced non‐small cell lung cancer

MET inhibitors have shown activity in non‐small‐cell lung cancer patients (NSCLC) with MET amplification and exon 14 skipping (METΔex14). However, patient stratification is imperfect, and thus, response rates have varied widely. Here, we studied MET alterations in 474 advanced NSCLC patients by nCou...

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Detalles Bibliográficos
Autores principales: Aguado, Cristina, Teixido, Cristina, Román, Ruth, Reyes, Roxana, Giménez‐Capitán, Ana, Marin, Elba, Cabrera, Carlos, Viñolas, Nuria, Castillo, Sergi, Muñoz, Silvia, Arcocha, Ainara, López‐Vilaró, Laura, Sullivan, Ivana, Aldeguer, Erika, Rodríguez, Sonia, Moya, Irene, Viteri, Santiago, Cardona, Andrés Felipe, Palmero, Ramon, Sainz, Cristina, Mesa‐Guzmán, Miguel, Lozano, Maria D., Aguilar‐Hernández, Andrés, Martínez‐Bueno, Alejandro, González‐Cao, María, Gonzalvo, Elena, Leenders, William P. J., Rosell, Rafael, Montuenga, Luis M., Prat, Aleix, Molina‐Vila, Miguel A., Reguart, Noemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7858100/
https://www.ncbi.nlm.nih.gov/pubmed/33236532
http://dx.doi.org/10.1002/1878-0261.12861