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Role of O‐linked N‐acetylglucosamine in the homeostasis of metabolic organs, and its potential links with diabetes and its complications
Recent studies using genetically manipulated mouse models have shown the pivotal role of O‐linked N‐acetylglucosamine modification (O‐GlcNAcylation) in the metabolism of multiple organs. The molecular mechanism involves the sensing of glucose flux by the hexosamine biosynthesis pathway, which leads...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7858115/ https://www.ncbi.nlm.nih.gov/pubmed/32654398 http://dx.doi.org/10.1111/jdi.13359 |