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Role of O‐linked N‐acetylglucosamine in the homeostasis of metabolic organs, and its potential links with diabetes and its complications

Recent studies using genetically manipulated mouse models have shown the pivotal role of O‐linked N‐acetylglucosamine modification (O‐GlcNAcylation) in the metabolism of multiple organs. The molecular mechanism involves the sensing of glucose flux by the hexosamine biosynthesis pathway, which leads...

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Detalles Bibliográficos
Autores principales:	Morino, Katsutaro, Maegawa, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7858115/ https://www.ncbi.nlm.nih.gov/pubmed/32654398 http://dx.doi.org/10.1111/jdi.13359

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