HRD1 inhibits fatty acid oxidation and tumorigenesis by ubiquitinating CPT2 in triple‐negative breast cancer

Dependence on glutamine and acceleration of fatty acid oxidation (FAO) are both metabolic characteristics of triple‐negative breast cancer (TNBC). With the rapid growth of tumors, accelerated glutamine catabolism depletes local glutamine, resulting in glutamine deficiency. Studies have shown that th...

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Detalles Bibliográficos
Autores principales: Guo, Xin, Wang, Aman, Wang, Wen, Wang, Ya, Chen, Huan, Liu, Xiaolong, Xia, Tian, Zhang, Aijia, Chen, Di, Qi, Huan, Ling, Ting, Piao, Hai‐long, Wang, Hong‐jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7858277/
https://www.ncbi.nlm.nih.gov/pubmed/33207079
http://dx.doi.org/10.1002/1878-0261.12856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7858277/
https://www.ncbi.nlm.nih.gov/pubmed/33207079
http://dx.doi.org/10.1002/1878-0261.12856

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