Genome‐scale CRISPR screening identifies cell cycle and protein ubiquitination processes as druggable targets for erlotinib‐resistant lung cancer

Erlotinib is highly effective in lung cancer patients with epidermal growth factor receptor (EGFR) mutations. However, despite initial favorable responses, most patients rapidly develop resistance to erlotinib soon after the initial treatment. This study aims to identify new genes and pathways assoc...

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Detalles Bibliográficos
Autores principales: Lee, Jieun, Choi, Ahyoung, Cho, Sung‐Yup, Jun, Yukyung, Na, Deukchae, Lee, Ahra, Jang, Giyong, Kwon, Jee Young, Kim, Jaesang, Lee, Sanghyuk, Lee, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7858278/
https://www.ncbi.nlm.nih.gov/pubmed/33188726
http://dx.doi.org/10.1002/1878-0261.12853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7858278/
https://www.ncbi.nlm.nih.gov/pubmed/33188726
http://dx.doi.org/10.1002/1878-0261.12853

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