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Repurposing antitussive benproperine phosphate against pancreatic cancer depends on autophagy arrest

Pancreatic cancer (PC) is one of the most common human malignancies worldwide and remains a major clinical challenge. Here, we found that benproperine phosphate (BPP), a cough suppressant, showed a significant anticancer effect on PC both in vitro and in vivo via the induction of autophagy‐mediated...

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Detalles Bibliográficos
Autores principales: Zhang, Huanyu, Zhang, Zhe, Huang, Yonghao, Qin, Siyuan, Zhou, Li, Weng, Ningna, Liu, Jiayang, Yang, Mei, Zhang, Xiaodian, Lu, Yanda, Ma, Lin, Zheng, Shaojiang, Li, Qifu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7858282/
https://www.ncbi.nlm.nih.gov/pubmed/33226737
http://dx.doi.org/10.1002/1878-0261.12854