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Cyclodextrin-based host-guest complexes loaded with regorafenib for colorectal cancer treatment

The malignancy of colorectal cancer (CRC) is connected with inflammation and tumor-associated macrophages (TAMs), but effective therapeutics for CRC are limited. To integrate therapeutic targeting with tumor microenvironment (TME) reprogramming, here we develop biocompatible, non-covalent channel-ty...

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Detalles Bibliográficos
Autores principales: Bai, Hongzhen, Wang, Jianwei, Phan, Chi Uyen, Chen, Qi, Hu, Xiurong, Shao, Guoqiang, Zhou, Jun, Lai, Lihua, Tang, Guping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7858623/
https://www.ncbi.nlm.nih.gov/pubmed/33536421
http://dx.doi.org/10.1038/s41467-021-21071-0