Cargando…

Bactericidal Permeability Increasing Protein Deficiency Aggravates Acute Colitis in Mice by Increasing the Serum Levels of Lipopolysaccharide

OBJECTIVE: The objective of this study was to understand the role of bactericidal permeability increasing protein (BPI) in the pathogenesis of experimental murine colitis. METHODS: We used the Cre-LoxP system to generate BPI knockout (BPI KO) mice. Acute colitis was induced in BPI KO mice and wild-t...

Descripción completa

Detalles Bibliográficos
Autores principales: Kong, Qingli, Lv, Zhe, Kang, Yun, An, Yunqing, Liu, Zhenlong, Zhang, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7858664/
https://www.ncbi.nlm.nih.gov/pubmed/33552078
http://dx.doi.org/10.3389/fimmu.2020.614169