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Bactericidal Permeability Increasing Protein Deficiency Aggravates Acute Colitis in Mice by Increasing the Serum Levels of Lipopolysaccharide

OBJECTIVE: The objective of this study was to understand the role of bactericidal permeability increasing protein (BPI) in the pathogenesis of experimental murine colitis. METHODS: We used the Cre-LoxP system to generate BPI knockout (BPI KO) mice. Acute colitis was induced in BPI KO mice and wild-t...

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Detalles Bibliográficos
Autores principales:	Kong, Qingli, Lv, Zhe, Kang, Yun, An, Yunqing, Liu, Zhenlong, Zhang, Jianmin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7858664/ https://www.ncbi.nlm.nih.gov/pubmed/33552078 http://dx.doi.org/10.3389/fimmu.2020.614169

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