Impaired Duodenal Palmitoylethanolamide Release Underlies Acid-Induced Mast Cell Activation in Functional Dyspepsia

BACKGROUND & AIMS: Acid hypersensitivity is claimed to be a symptomatic trigger in functional dyspepsia (FD); however, the neuroimmune pathway(s) and the mediators involved in this process have not been investigated systematically. Palmitoylethanolamide (PEA) is an endogenous compound, able to m...

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Detalles Bibliográficos
Autores principales: Sarnelli, Giovanni, Pesce, Marcella, Seguella, Luisa, Lu, Jie, Efficie, Eleonora, Tack, Jan, Elisa De Palma, Fatima Domenica, D’Alessandro, Alessandra, Esposito, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7858681/
https://www.ncbi.nlm.nih.gov/pubmed/33065341
http://dx.doi.org/10.1016/j.jcmgh.2020.10.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7858681/
https://www.ncbi.nlm.nih.gov/pubmed/33065341
http://dx.doi.org/10.1016/j.jcmgh.2020.10.001

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