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Calcipotriol/Betamethasone Dipropionate Foam Inhibits Th17 Cytokine Secretion and Improves Epidermal Barrier Markers in a Human Th17 Skin Inflammation Model

INTRODUCTION: T-helper 17 (Th17) cytokines play a key role in the pathophysiology of psoriasis by driving inflammatory responses that lead to epidermal alterations. Markers of epidermal differentiation, including the proteins loricrin (LOR), filaggrin (FLG) and involucrin (IVL), are dysregulated in...

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Detalles Bibliográficos
Autores principales: Lovato, Paola, Jiang, Li, Hebsgaard, Josephine, Ewald, David A., Norsgaard, Hanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859006/
https://www.ncbi.nlm.nih.gov/pubmed/33458806
http://dx.doi.org/10.1007/s13555-020-00482-9