Cargando…
Activation of the Nlrp3 Inflammasome Contributes to Shiga Toxin-Induced Hemolytic Uremic Syndrome in a Mouse Model
OBJECTIVE: To explore the role of the Nlrp3 inflammasome activation in the development of hemolytic uremic syndrome (HUS) induced by Stx2 and evaluate the efficacy of small molecule Nlrp3 inhibitors in preventing the HUS. METHODS: Peritoneal macrophages (PMs) isolated from wild-type (WT) C57BL/6J mi...
Autores principales: | Song, Liqiong, Xiao, Yuchun, Li, Xianping, Huang, Yuanming, Meng, Guangxun, Ren, Zhihong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859089/ https://www.ncbi.nlm.nih.gov/pubmed/33552083 http://dx.doi.org/10.3389/fimmu.2020.619096 |
Ejemplares similares
-
Contribution of Nlrp3 Inflammasome Activation Mediated by Suilysin to Streptococcal Toxic Shock-like Syndrome
por: Song, Liqiong, et al.
Publicado: (2020) -
Heme as Possible Contributing Factor in the Evolvement of Shiga-Toxin Escherichia coli Induced Hemolytic-Uremic Syndrome
por: Wijnsma, Kioa L., et al.
Publicado: (2020) -
Complement Activation Contributes to the Pathophysiology of Shiga Toxin-Associated Hemolytic Uremic Syndrome
por: Buelli, Simona, et al.
Publicado: (2019) -
Cardiovascular impairment in Shiga-toxin-2-induced experimental hemolytic–uremic syndrome: a pilot study
por: Neu, Charles, et al.
Publicado: (2023) -
Shiga Toxins and the Pathophysiology of Hemolytic Uremic Syndrome in Humans and Animals
por: Mayer, Chad L., et al.
Publicado: (2012)