The heptamer sgRNA targeting the human OCT4 mRNA can upregulate the OCT4 expression

TRUE gene silencing is one of the gene suppression technologies. This technology exploits the enzymatic property of the tRNA 3′ processing endoribonuclease tRNase Z(L), which is that it can cleave a target RNA under the direction of a small guide RNA (sgRNA). We have been working on the development...

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Detalles Bibliográficos
Autores principales: Nozaki, Tadasuke, Takahashi, Masayuki, Ishikawa, Tatsuya, Haino, Arisa, Seki, Mineaki, Kikuchi, Hidetomo, Yuan, Bo, Nashimoto, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859166/
https://www.ncbi.nlm.nih.gov/pubmed/33553691
http://dx.doi.org/10.1016/j.bbrep.2021.100918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859166/
https://www.ncbi.nlm.nih.gov/pubmed/33553691
http://dx.doi.org/10.1016/j.bbrep.2021.100918

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