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The heptamer sgRNA targeting the human OCT4 mRNA can upregulate the OCT4 expression
TRUE gene silencing is one of the gene suppression technologies. This technology exploits the enzymatic property of the tRNA 3′ processing endoribonuclease tRNase Z(L), which is that it can cleave a target RNA under the direction of a small guide RNA (sgRNA). We have been working on the development...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859166/ https://www.ncbi.nlm.nih.gov/pubmed/33553691 http://dx.doi.org/10.1016/j.bbrep.2021.100918 |