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Druggable targets meet oncogenic drivers: opportunities and limitations of target-based classification of tumors and the role of Molecular Tumor Boards

The therapeutic landscape of cancer is changing rapidly due to the growing number of approved drugs capable of targeting specific genetic alterations. This aspect, together with the development of noninvasive methods for the assessment of somatic mutations in the peripheral blood of patients, genera...

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Detalles Bibliográficos
Autores principales: Danesi, R., Fogli, S., Indraccolo, S., Del Re, M., Dei Tos, A.P., Leoncini, L., Antonuzzo, L., Bonanno, L., Guarneri, V., Pierini, A., Amunni, G., Conte, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859305/
https://www.ncbi.nlm.nih.gov/pubmed/33540286
http://dx.doi.org/10.1016/j.esmoop.2020.100040