Cargando…
Druggable targets meet oncogenic drivers: opportunities and limitations of target-based classification of tumors and the role of Molecular Tumor Boards
The therapeutic landscape of cancer is changing rapidly due to the growing number of approved drugs capable of targeting specific genetic alterations. This aspect, together with the development of noninvasive methods for the assessment of somatic mutations in the peripheral blood of patients, genera...
Autores principales: | Danesi, R., Fogli, S., Indraccolo, S., Del Re, M., Dei Tos, A.P., Leoncini, L., Antonuzzo, L., Bonanno, L., Guarneri, V., Pierini, A., Amunni, G., Conte, P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859305/ https://www.ncbi.nlm.nih.gov/pubmed/33540286 http://dx.doi.org/10.1016/j.esmoop.2020.100040 |
Ejemplares similares
-
The Tumor Microenvironment: A Druggable Target for Metastatic Disease?
por: EBioMedicine
Publicado: (2018) -
Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors
por: Infante, Paola, et al.
Publicado: (2015) -
Uncovering Potential Therapeutic Targets in Colorectal Cancer by Deciphering Mutational Status and Expression of Druggable Oncogenes
por: Menyhart, Otília, et al.
Publicado: (2019) -
Kinases
as Druggable Targets in Trypanosomatid Protozoan
Parasites
por: Merritt, Christopher, et al.
Publicado: (2014) -
Beyond finding druggable targets and tumor mutational burden: to measure heterogeneity by ctDNA
por: Liu, Zhichao, et al.
Publicado: (2020)