Shelterin complex gene: Prognosis and therapeutic vulnerability in cancer()

Telomere encompasses a (TTAGGG)n tandem repeats, and its dysfunction has emerged as the epicenter of driving carcinogenesis by promoting genetic instability. Indeed, they play an essential role in stabilizing chromosomes and therefore protecting them from end-to-end fusion and DNA degradation. Telom...

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Detalles Bibliográficos
Autores principales: Bhari, Vikas Kumar, Kumar, Durgesh, Kumar, Surendra, Mishra, Rajeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859307/
https://www.ncbi.nlm.nih.gov/pubmed/33553693
http://dx.doi.org/10.1016/j.bbrep.2021.100937

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859307/
https://www.ncbi.nlm.nih.gov/pubmed/33553693
http://dx.doi.org/10.1016/j.bbrep.2021.100937

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