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Calcium Signaling in T Cells Is Induced by Binding to Nickel-Chelating Lipids in Supported Lipid Bilayers

Supported lipid bilayers (SLBs) are one of the most common cell-membrane model systems to study cell-cell interactions. Nickel-chelating lipids are frequently used to functionalize the SLB with polyhistidine-tagged ligands. We show here that these lipids by themselves can induce calcium signaling in...

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Detalles Bibliográficos
Autores principales: Dam, Tommy, Junghans, Victoria, Humphrey, Jane, Chouliara, Manto, Jönsson, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859345/
https://www.ncbi.nlm.nih.gov/pubmed/33551841
http://dx.doi.org/10.3389/fphys.2020.613367