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Shear Stress Rescued the Neuronal Impairment Induced by Global Cerebral Ischemia Reperfusion via Activating PECAM-1-eNOS-NO Pathway

Microvessel hypoperfusion following ischemic stress resulted in a decreased shear stress of brain microvascular endothelial cells (BMECs) and contributed to abnormal expression of PECAM-1 after global cerebral ischemia/reperfusion (I/R) injury. Here, we identified novel pathophysiologic and rehabili...

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Detalles Bibliográficos
Autores principales: Gao, Jing-Quan, Wang, Peng, Yan, Jun-Wei, Ba, Li-Na, Shi, Pi-Long, Wu, Hong-Mei, Guan, Xue-Ying, Cao, Yong-gang, Sun, Hong-Li, Mao, Xiao-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859356/
https://www.ncbi.nlm.nih.gov/pubmed/33553171
http://dx.doi.org/10.3389/fcell.2020.631286