RasGRP2 inhibits glyceraldehyde-derived toxic advanced glycation end-products from inducing permeability in vascular endothelial cells

Advanced glycation end-products (AGEs) are formed by the non-enzymatic reaction of sugars and proteins. Among the AGEs, glyceraldehyde-derived toxic AGEs (TAGE) are associated with various diseases, including diabetic complications such as diabetic retinopathy (DR). The risk of developing DR is stro...

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Detalles Bibliográficos
Autores principales: Takino, Jun-ichi, Sato, Takuma, Kanetaka, Takumi, Okihara, Kasumi, Nagamine, Kentaro, Takeuchi, Masayoshi, Hori, Takamitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859393/
https://www.ncbi.nlm.nih.gov/pubmed/33536515
http://dx.doi.org/10.1038/s41598-021-82619-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859393/
https://www.ncbi.nlm.nih.gov/pubmed/33536515
http://dx.doi.org/10.1038/s41598-021-82619-0

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