l-Isoaspartyl Methyltransferase Deficiency in Zebrafish Leads to Impaired Calcium Signaling in the Brain

Isomerization of l-aspartyl and l-asparaginyl residues to l-isoaspartyl residues is one type of protein damage that can occur under physiological conditions and leads to conformational changes, loss of function, and enhanced protein degradation. Protein l-isoaspartyl methyltransferase (PCMT) is a re...

Descripción completa

Detalles Bibliográficos
Autores principales: Soliman, Remon, Cordero-Maldonado, Maria Lorena, Martins, Teresa G., Moein, Mahsa, Conrotte, Jean-François, Warmack, Rebeccah A., Skupin, Alexander, Crawford, Alexander D., Clarke, Steven G., Linster, Carole L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859441/
https://www.ncbi.nlm.nih.gov/pubmed/33552132
http://dx.doi.org/10.3389/fgene.2020.612343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859441/
https://www.ncbi.nlm.nih.gov/pubmed/33552132
http://dx.doi.org/10.3389/fgene.2020.612343

Ejemplares similares