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l-Isoaspartyl Methyltransferase Deficiency in Zebrafish Leads to Impaired Calcium Signaling in the Brain

Isomerization of l-aspartyl and l-asparaginyl residues to l-isoaspartyl residues is one type of protein damage that can occur under physiological conditions and leads to conformational changes, loss of function, and enhanced protein degradation. Protein l-isoaspartyl methyltransferase (PCMT) is a re...

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Detalles Bibliográficos
Autores principales:	Soliman, Remon, Cordero-Maldonado, Maria Lorena, Martins, Teresa G., Moein, Mahsa, Conrotte, Jean-François, Warmack, Rebeccah A., Skupin, Alexander, Crawford, Alexander D., Clarke, Steven G., Linster, Carole L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859441/ https://www.ncbi.nlm.nih.gov/pubmed/33552132 http://dx.doi.org/10.3389/fgene.2020.612343

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