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Alternative polyadenylation of mRNA and its role in cancer

Alternative polyadenylation (APA) is a molecular process that generates diversity at the 3′ end of RNA polymerase II transcripts from over 60% of human genes. APA is derived from the existence of multiple polyadenylation signals (PAS) within the same transcript, and results in the differential inclu...

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Detalles Bibliográficos
Autores principales: Yuan, Fuwen, Hankey, William, Wagner, Eric J., Li, Wei, Wang, Qianben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859462/
https://www.ncbi.nlm.nih.gov/pubmed/33569514
http://dx.doi.org/10.1016/j.gendis.2019.10.011