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Recombinant immunotoxin targeting GPC3 is cytotoxic to H446 small cell lung cancer cells
Glypican-3 (GPC3) is a cell membrane glycoprotein that regulates cell growth and proliferation. Aberrant expression or distribution of GPC3 underlies developmental abnormalities and the development of solid tumours. The strongest evidence for the participation of GPC3 in carcinogenesis stems from st...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859473/ https://www.ncbi.nlm.nih.gov/pubmed/33613711 http://dx.doi.org/10.3892/ol.2021.12483 |