Microengineered systems with iPSC-derived cardiac and hepatic cells to evaluate drug adverse effects

Hepatic and cardiac drug adverse effects are among the leading causes of attrition in drug development programs, in part due to predictive failures of current animal or in vitro models. Hepatocytes and cardiomyocytes differentiated from human induced pluripotent stem cells (iPSCs) hold promise for p...

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Detalles Bibliográficos
Autores principales: Dame, Keri, Ribeiro, Alexandre JS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859673/
https://www.ncbi.nlm.nih.gov/pubmed/32938227
http://dx.doi.org/10.1177/1535370220959598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859673/
https://www.ncbi.nlm.nih.gov/pubmed/32938227
http://dx.doi.org/10.1177/1535370220959598

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