Mutant Cx30-A88V mice exhibit hydrocephaly and sex-dependent behavioral abnormalities, implicating a functional role for Cx30 in the brain

Connexin 30 (Cx30; also known as Gjb6 when referring to the mouse gene) is expressed in ependymal cells of the brain ventricles, in leptomeningeal cells and in astrocytes rich in connexin 43 (Cx43), leading us to question whether patients harboring GJB6 mutations exhibit any brain anomalies. Here, w...

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Detalles Bibliográficos
Autores principales: Novielli-Kuntz, Nicole M., Press, Eric R., Barr, Kevin, Prado, Marco A. M., Laird, Dale W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859702/
https://www.ncbi.nlm.nih.gov/pubmed/33735099
http://dx.doi.org/10.1242/dmm.046235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859702/
https://www.ncbi.nlm.nih.gov/pubmed/33735099
http://dx.doi.org/10.1242/dmm.046235

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