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Epigallocatechin-3-gallate, an active ingredient of Traditional Chinese Medicines, inhibits the 3CLpro activity of SARS-CoV-2

SARS-CoV-2 is the etiological agent responsible for the ongoing pandemic of coronavirus disease 2019 (COVID-19). The main protease of SARS-CoV-2, 3CLpro, is an attractive target for antiviral inhibitors due to its indispensable role in viral replication and gene expression of viral proteins. The sea...

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Detalles Bibliográficos
Autores principales: Du, Ashuai, Zheng, Rong, Disoma, Cyrollah, Li, Shiqin, Chen, Zongpeng, Li, Sijia, Liu, Pinjia, Zhou, Yuzheng, Shen, Yilun, Liu, Sixu, Zhang, Yongxing, Dong, Zijun, Yang, Qinglong, Alsaadawe, Moyed, Razzaq, Aroona, Peng, Yuyang, Chen, Xuan, Hu, Liqiang, Peng, Jian, Zhang, Qianjun, Jiang, Taijiao, Mo, Long, Li, Shanni, Xia, Zanxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859723/
https://www.ncbi.nlm.nih.gov/pubmed/33548314
http://dx.doi.org/10.1016/j.ijbiomac.2021.02.012