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Angiopoietin-2 outperforms other endothelial biomarkers associated with severe acute kidney injury in patients with severe sepsis and respiratory failure

BACKGROUND: Endothelial dysfunction and injury is a major pathophysiologic feature of sepsis. Sepsis is also the most frequent cause of acute kidney injury (AKI) in critically ill patients. Though most studies of AKI in sepsis have focused on tubular epithelial injury, the role of endothelial dysfun...

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Detalles Bibliográficos
Autores principales: Yu, Wen-Kuang, McNeil, J. Brennan, Wickersham, Nancy E., Shaver, Ciara M., Bastarache, Julie A., Ware, Lorraine B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859898/
https://www.ncbi.nlm.nih.gov/pubmed/33541396
http://dx.doi.org/10.1186/s13054-021-03474-z