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Use of miR-145 and testicular nuclear receptor 4 inhibition to reduce chemoresistance to docetaxel in prostate cancer

The human testicular nuclear receptor 4 (TR4) is a critical regulatory gene for the progression of prostate cancer (PCa). Although it has been revealed that TR4 causes chemoresistance in PCa via the activation of octamer-binding transcription factor 4 (OCT4), the detailed mechanism remains unexplore...

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Detalles Bibliográficos
Autores principales: Zhu, Jin, Qin, Peibo, Cao, Cheng, Dai, Guangcheng, Xu, Lijun, Yang, Dongrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859919/
https://www.ncbi.nlm.nih.gov/pubmed/33650661
http://dx.doi.org/10.3892/or.2021.7925